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What do we learn from HER2-positive breast cancer genomic profiles?

Patients with a tumor presenting amplification of the HER2 gene are currently proposed trastuzumab (herceptin) and this has greatly changed their outcome. However, a number of HER2-positive cancers show intrinsic or acquired resistance to trastuzumab and there are clear indications that they form a...

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Dades bibliogràfiques
Autor principal: Theillet, Charles
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917015/
https://ncbi.nlm.nih.gov/pubmed/20519027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2571
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