Biological and Structural Characterization of a Host-Adapting Amino Acid in Influenza Virus

Two amino acids (lysine at position 627 or asparagine at position 701) in the polymerase subunit PB2 protein are considered critical for the adaptation of avian influenza A viruses to mammals. However, the recently emerged pandemic H1N1 viruses lack these amino acids. Here, we report that a basic am...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Yamada, Shinya, Hatta, Masato, Staker, Bart L., Watanabe, Shinji, Imai, Masaki, Shinya, Kyoko, Sakai-Tagawa, Yuko, Ito, Mutsumi, Ozawa, Makoto, Watanabe, Tokiko, Sakabe, Saori, Li, Chengjun, Kim, Jin Hyun, Myler, Peter J., Phan, Isabelle, Raymond, Amy, Smith, Eric, Stacy, Robin, Nidom, Chairul A., Lank, Simon M., Wiseman, Roger W., Bimber, Benjamin N., O'Connor, David H., Neumann, Gabriele, Stewart, Lance J., Kawaoka, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916879/
https://ncbi.nlm.nih.gov/pubmed/20700447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001034
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados