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Structure-based kernels for the prediction of catalytic residues and their involvement in human inherited disease

Motivation: Enzyme catalysis is involved in numerous biological processes and the disruption of enzymatic activity has been implicated in human disease. Despite this, various aspects of catalytic reactions are not completely understood, such as the mechanics of reaction chemistry and the geometry of...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Xin, Fuxiao, Myers, Steven, Li, Yong Fuga, Cooper, David N., Mooney, Sean D., Radivojac, Predrag
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916715/
https://ncbi.nlm.nih.gov/pubmed/20551136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq319
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