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Structure-based kernels for the prediction of catalytic residues and their involvement in human inherited disease
Motivation: Enzyme catalysis is involved in numerous biological processes and the disruption of enzymatic activity has been implicated in human disease. Despite this, various aspects of catalytic reactions are not completely understood, such as the mechanics of reaction chemistry and the geometry of...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916715/ https://ncbi.nlm.nih.gov/pubmed/20551136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq319 |
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