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Structure-based kernels for the prediction of catalytic residues and their involvement in human inherited disease

Motivation: Enzyme catalysis is involved in numerous biological processes and the disruption of enzymatic activity has been implicated in human disease. Despite this, various aspects of catalytic reactions are not completely understood, such as the mechanics of reaction chemistry and the geometry of...

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Detalhes bibliográficos
Principais autores: Xin, Fuxiao, Myers, Steven, Li, Yong Fuga, Cooper, David N., Mooney, Sean D., Radivojac, Predrag
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916715/
https://ncbi.nlm.nih.gov/pubmed/20551136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq319
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