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Polycystic kidney disease protein fibrocystin localizes to the mitotic spindle and regulates spindle bipolarity

Autosomal recessive polycystic kidney disease (ARPKD) is a significant hereditary renal disease occurring in infancy and childhood, which presents with greatly enlarged echogenic kidneys, ultimately leading to renal insufficiency and end-stage renal disease. ARPKD is caused by mutations in a single...

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Detalhes bibliográficos
Main Authors: Zhang, Jingjing, Wu, Maoqing, Wang, Shixuan, Shah, Jagesh V., Wilson, Patricia D., Zhou, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916704/
https://ncbi.nlm.nih.gov/pubmed/20554582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq233
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