Major histocompatibility complex (MHC) class II alleles, haplotypes and epitopes which confer susceptibility or protection in systemic sclerosis: analyses in 1300 Caucasian, African-American and Hispanic cases and 1000 controls

OBJECTIVE: To determine human leucocyte antigen-class II (HLA-class II) (DRB1, DQB1, DQA1 and DPB1) alleles, haplotypes and shared epitopes associated with scleroderma (systemic sclerosis (SSc)) and its subphenotypes in a large multi-ethnic US cohort by a case–control association study. PATIENTS AND...

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Bibliographic Details
Main Authors: Arnett, Frank C, Gourh, Pravitt, Shete, Sanjay, Ahn, Chul W, Honey, Robert E, Agarwal, Sandeep K, Tan, Filemon K, McNearney, Terry, Fischbach, Michael, Fritzler, Marvin J, Mayes, Maureen D, Reveille, John D
Format: Artigo
Language:Inglês
Published: BMJ Group 2010
Subjects:
Clinical and Epidemiological Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916702/
https://ncbi.nlm.nih.gov/pubmed/19596691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2009.111906
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