Dephosphorylation of F-BAR protein Cdc15 modulates its conformation and stimulates its scaffolding activity at the cell division site

Cytokinesis in Schizosaccharomyces pombe requires the function of Cdc15, founding member of the pombe cdc15 homology (PCH) family of proteins. As an early, abundant contractile ring component with multiple binding partners, Cdc15 plays a key role in organizing the ring. We demonstrate that Cdc15 pho...

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Hoofdauteurs: Roberts-Galbraith, Rachel H., Ohi, Melanie D., Ballif, Bryan A., Chen, Jun-Song, McLeod, Ian, McDonald, W. Hayes, Gygi, Steven P., Yates, John R., Gould, Kathleen L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916701/
https://ncbi.nlm.nih.gov/pubmed/20603077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.06.012
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