Evaluation of the Roche Cobas AmpliPrep/Cobas TaqMan HIV-1 Test and Identification of Rare Polymorphisms Potentially Affecting Assay Performance

We evaluated the FDA-approved Roche Cobas AmpliPrep/Cobas TaqMan (CAP/CTM) HIV-1 viral load assay for sensitivity, reproducibility, linearity, HIV-1 subtype detection, and correlation to the Roche Amplicor HIV-1 monitor test, version 1.5 (Amplicor). The limit of detection calculated by probit analys...

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Bibliographic Details
Main Authors: Pyne, Michael T., Brown, Katherine L., Hillyard, David R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Virology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916612/
https://ncbi.nlm.nih.gov/pubmed/20573864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00776-10
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