Clinical Performance of the PreTect HPV-Proofer E6/E7 mRNA Assay in Comparison with That of the Hybrid Capture 2 Test for Identification of Women at Risk of Cervical Cancer

Human papillomavirus (HPV) DNA testing has a higher clinical sensitivity than cytology for the detection of high-grade cervical intraepithelial neoplasia or worse (CIN 2+). However, an improvement in specificity would be desirable. As malignant transformation is induced by HPV E6/E7 oncogenes, detec...

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Hlavní autoři: Ratnam, Samuel, Coutlee, Francois, Fontaine, Dan, Bentley, James, Escott, Nicholas, Ghatage, Prafull, Gadag, Veeresh, Holloway, Glen, Bartellas, Elias, Kum, Nick, Giede, Christopher, Lear, Adrian
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Virology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916571/
https://ncbi.nlm.nih.gov/pubmed/20573862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00382-10
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