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Novel Florfenicol and Chloramphenicol Resistance Gene Discovered in Alaskan Soil by Using Functional Metagenomics

Functional metagenomics was used to search for florfenicol resistance genes in libraries of cloned DNA isolated from Alaskan soil. A gene that mediated reduced susceptibility to florfenicol was identified and designated pexA. The predicted PexA protein showed a structure similar to that of efflux pu...

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Main Authors: Lang, Kevin S., Anderson, Janet M., Schwarz, Stefan, Williamson, Lynn, Handelsman, Jo, Singer, Randall S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916469/
https://ncbi.nlm.nih.gov/pubmed/20543056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00323-10
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