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Domain-Specific Response of Imprinted Genes to Reduced DNMT1

Imprinted genes are expressed in a monoallelic, parent-of-origin-specific manner. Clusters of imprinted genes are regulated by imprinting control regions (ICRs) characterized by DNA methylation of one allele. This methylation is critical for imprinting; a reduction in the DNA methyltransferase DNMT1...

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Detalhes bibliográficos
Main Authors: Weaver, Jamie R., Sarkisian, Garnik, Krapp, Christopher, Mager, Jesse, Mann, Mellissa R. W., Bartolomei, Marisa S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916450/
https://ncbi.nlm.nih.gov/pubmed/20547750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01278-09
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