In Vitro Reconstitution of PHO5 Promoter Chromatin Remodeling Points to a Role for Activator-Nucleosome Competition In Vivo

The yeast PHO5 promoter is a classical model for studying the role of chromatin in gene regulation. To enable biochemical dissection of the mechanism leading to PHO5 activation, we reconstituted the process in vitro. Positioned nucleosomes corresponding to the repressed PHO5 promoter state were asse...

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Hlavní autoři: Ertel, Franziska, Dirac-Svejstrup, A. Barbara, Hertel, Christina Bech, Blaschke, Dorothea, Svejstrup, Jesper Q., Korber, Philipp
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916437/
https://ncbi.nlm.nih.gov/pubmed/20566699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01399-09
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