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The Native 67-Kilodalton Minor Fimbria of Porphyromonas gingivalis Is a Novel Glycoprotein with DC-SIGN-Targeting Motifs

We recently reported that the oral mucosal pathogen Porphyromonas gingivalis, through its 67-kDa Mfa1 (minor) fimbria, targets the C-type lectin receptor DC-SIGN for invasion and persistence within human monocyte-derived dendritic cells (DCs). The DCs respond by inducing an immunosuppressive and Th2...

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Bibliografiske detaljer
Main Authors: Zeituni, Amir E., McCaig, William, Scisci, Elizabeth, Thanassi, David G., Cutler, Christopher W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916435/
https://ncbi.nlm.nih.gov/pubmed/20562309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00275-10
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