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CcpA Mediates Proline Auxotrophy and Is Required for Staphylococcus aureus Pathogenesis

Human clinical isolates of Staphylococcus aureus, for example, strains Newman and N315, cannot grow in the absence of proline, albeit their sequenced genomes harbor genes for two redundant proline synthesis pathways. We show here that under selective pressure, S. aureus Newman generates proline-prot...

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Autores principales: Li, Chunling, Sun, Fei, Cho, Hoonsik, Yelavarthi, Vamshi, Sohn, Changmo, He, Chuan, Schneewind, Olaf, Bae, Taeok
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916365/
https://ncbi.nlm.nih.gov/pubmed/20525824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00237-10
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