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In Vitro System for Modeling Influenza A Virus Resistance under Drug Pressure

One of the biggest challenges in the effort to treat and contain influenza A virus infections is the emergence of resistance during treatment. It is well documented that resistance to amantadine arises rapidly during the course of treatment due to mutations in the gene coding for the M2 protein. To...

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Autori principali: Brown, Ashley N., McSharry, James J., Weng, Qingmei, Driebe, Elizabeth M., Engelthaler, David M., Sheff, Kelly, Keim, Paul S., Nguyen, Jack, Drusano, George L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916361/
https://ncbi.nlm.nih.gov/pubmed/20498316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01385-09
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