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Enrichment of Auxotrophic Mutants in Streptomyces griseus

A method for the isolation and enrichment of tryptophan auxotrophic mutants of the indolmycin-producing strain Streptomyces griseus ATCC 12648 was developed, using penicillin selection. With UV irradiation of 2.2 × 10(4) μW cm(−2), a mutation rate to tryptophan auxotrophy of 5.6 × 10(−4) was achieve...

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Bibliografiske detaljer
Main Authors: Werner, Rolf G., Demain, Arnold L.
Format: Artigo
Sprog:Inglês
Udgivet: 1980
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC291636/
https://ncbi.nlm.nih.gov/pubmed/16345642
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