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Pharmacokinetics and Safety of CXA-101, a New Antipseudomonal Cephalosporin, in Healthy Adult Male and Female Subjects Receiving Single- and Multiple-Dose Intravenous Infusions

CXA-101 is a novel, broad-spectrum cephalosporin with excellent antipseudomonal activity. A Phase 1 study was performed to determine the safety, tolerability, and pharmacokinetics of CXA-101 after single- and multiple-dose intravenous administration over 1 h to healthy male and female subjects. In p...

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Detalhes bibliográficos
Main Authors: Ge, Yigong, Whitehouse, M. J., Friedland, Ian, Talbot, George H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916350/
https://ncbi.nlm.nih.gov/pubmed/20457817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01753-09
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