Daptomycin-Oxacillin Combinations in Treatment of Experimental Endocarditis Caused by Daptomycin-Nonsusceptible Strains of Methicillin-Resistant Staphylococcus aureus with Evolving Oxacillin Susceptibility (the “Seesaw Effect”)

In vivo development of daptomycin resistance (DAP(r)) among Staphylococcus aureus strains, especially methicillin-resistant S. aureus (MRSA) strains, in conjunction with clinical treatment failures, has emerged as a major problem. This has raised the question of DAP-based combination regimens to enh...

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Bibliographische Detailangaben
Hauptverfasser: Yang, Soo-Jin, Xiong, Yan Q., Boyle-Vavra, Susan, Daum, Robert, Jones, Tiffanny, Bayer, Arnold S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Mechanisms of Resistance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916313/
https://ncbi.nlm.nih.gov/pubmed/20547804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00487-10
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