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Translocation of Porphyromonas gingivalis Gingipain Adhesin Peptide A44 to Host Mitochondria Prevents Apoptosis

Porphyromonas gingivalis, a Gram-negative oral anaerobe, is associated with periodontal diseases that, in some form, affect up to 80% of the U.S. population. The organism is highly proteolytic, and noncatalytic adhesin domains of the major proteases, gingipains, are involved in bacterium-host intera...

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Bibliografiske detaljer
Main Authors: Boisvert, Heike, Duncan, Margaret J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916282/
https://ncbi.nlm.nih.gov/pubmed/20547744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00187-10
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