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Prevention of Escherichia coli K1 Penetration of the Blood-Brain Barrier by Counteracting the Host Cell Receptor and Signaling Molecule Involved in E. coli Invasion of Human Brain Microvascular Endothelial Cells

Escherichia coli meningitis is an important cause of mortality and morbidity, and a key contributing factor is our incomplete understanding of the pathogenesis of E. coli meningitis. We have shown that E. coli penetration into the brain requires E. coli invasion of human brain microvascular endothel...

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Detalhes bibliográficos
Main Authors: Zhu, Longkun, Pearce, Donna, Kim, Kwang Sik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916274/
https://ncbi.nlm.nih.gov/pubmed/20515928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00336-10
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