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Tumor masses support naive T cell infiltration, activation, and differentiation into effectors
Studies of T cell responses to tumors have focused on the draining lymph node (LN) as the site of activation. We examined the tumor mass as a potential site of activation after adoptive transfer of naive tumor-specific CD8 T cells. Activated CD8 T cells were present in tumors within 24 h of adoptive...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916130/ https://ncbi.nlm.nih.gov/pubmed/20660615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20092454 |
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