Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2

Cardiac atrial natriuretic peptide (ANP) locally counteracts cardiac hypertrophy via the guanylyl cyclase-A (GC-A) receptor and cGMP production, but the downstream signalling pathways are unknown. Here, we examined the influence of ANP on β-adrenergic versus Angiotensin II (Ang II)-dependent (G(s) v...

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Detalhes bibliográficos
Main Authors: Klaiber, Michael, Kruse, Martin, Völker, Katharina, Schröter, Juliane, Feil, Robert, Freichel, Marc, Gerling, Andrea, Feil, Susanne, Dietrich, Alexander, Londoño, Juan Eduardo Camacho, Baba, Hideo A., Abramowitz, Joel, Birnbaumer, Lutz, Penninger, Josef M., Pongs, Olaf, Kuhn, Michaela
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
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Original Contribution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916114/
https://ncbi.nlm.nih.gov/pubmed/20352235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-010-0098-z
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