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(−)-Epigallocatechin-3-gallate inhibits Met signaling, proliferation, and invasiveness in human colon cancer cells

The Met receptor tyrosine kinase is deregulated in a variety of cancers and is correlated with advanced stage and poor prognosis. Thus, Met has been identified as an attractive candidate for targeted therapy. We compared the tea polyphenol (−)-epigallocatechin-3-gallate (EGCG) and a specific Met inh...

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Detalhes bibliográficos
Main Authors: Larsen, Christine A., Dashwood, Roderick H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916072/
https://ncbi.nlm.nih.gov/pubmed/20361925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2010.03.017
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