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Resistance of Leishmania (Viannia) braziliensis to nitric oxide: correlation with antimony therapy and TNF-α production

BACKGROUND: Nitric oxide (NO) produced in macrophages plays a pivotal role as a leishmanicidal agent. A previous study has demonstrated that 20% of the L. (V.) braziliensis isolated from initial cutaneous lesions of patients from the endemic area of Corte de Pedra, Bahia, Brazil, were NO resistant....

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Autors principals: Souza, Anselmo S, Giudice, Angela, Pereira, Júlia MB, Guimarães, Luís H, de Jesus, Amelia R, de Moura, Tatiana R, Wilson, Mary E, Carvalho, Edgar M, Almeida, Roque P
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915995/
https://ncbi.nlm.nih.gov/pubmed/20633260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-10-209
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