TNFRSF1B A1466G genotype is predictive of clinical efficacy after treatment with a definitive 5-fluorouracil/cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma

BACKGROUND: Currently definitive 5-fluorouracil (5-FU)/cisplatin (CDDP) -based chemotherapy is recognized as one of the most promising treatments for esophageal cancer. A series of studies performed found genetic polymorphisms and the plasma concentration of 5-FU to be predictive of acute severe tox...

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Main Authors: Kuwahara, Akiko, Yamamori, Motohiro, Fujita, Megumi, Okuno, Tatsuya, Tamura, Takao, Kadoyama, Kaori, Okamura, Noboru, Nakamura, Tsutomu, Sakaeda, Toshiyuki
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915971/
https://ncbi.nlm.nih.gov/pubmed/20646319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-29-100
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