Calpain 3 Is a Rapid-Action, Unidirectional Proteolytic Switch Central to Muscle Remodeling

Calpain 3 (CAPN3) is a cysteine protease that when mutated causes Limb Girdle Muscular Dystrophy 2A. It is thereby the only described Calpain family member that genetically causes a disease. Due to its inherent instability little is known of its substrates or its mechanism of activity and pathogenic...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: de Morrée, Antoine, Lutje Hulsik, David, Impagliazzo, Antonietta, van Haagen, Herman H. H. B. M., de Galan, Paula, van Remoortere, Alexandra, 't Hoen, Peter A. C., van Ommen, GertJan B., Frants, Rune R., van der Maarel, Silvère M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915920/
https://ncbi.nlm.nih.gov/pubmed/20694146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011940
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados