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Higher expression of Bax in regulatory T cells increases vascular inflammation

This study is to examine our hypothesis that CD4+CD25(high)Foxp3+ regulatory T cells (Tregs) have an interleukin-2 (IL-2) withdrawal-triggered apoptosis pathway, and modulation of Treg apoptosis pathway affects development of vascular inflammation. We found that pro-apoptotic protein Bax upregulatio...

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Main Authors: Xiong, Zeyu, Song, Jian, Yan, Yan, Huang, Yajue, Cowan, Alan, Wang, Hong, Yang, Xiao-Feng
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915779/
https://ncbi.nlm.nih.gov/pubmed/18508723
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