Effect of VPAC1 Blockade on Adipose Tissue Formation and Composition in Mouse Models of Nutritionally Induced Obesity

Background. The pituitary adenylate cyclase activating polypeptide (PACAP) may affect adipogenesis and adipose tissue formation through interaction with its G-protein-coupled receptor VPAC1. Methods. We have used a monoclonal antibody (MAb 23A11) blocking VPAC1 in mouse models of nutritionally induc...

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Bibliographic Details
Main Authors: Lijnen, H. Roger, Freson, Kathleen, Hoylaerts, Marc F.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915750/
https://ncbi.nlm.nih.gov/pubmed/20721340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/359527
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