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Identification of a Novel in Vivo Virus-targeted Phosphorylation Site in Interferon Regulatory Factor-3 (IRF3)

The transcription factor interferon regulatory factor-3 (IRF3) regulates expression of type I interferon-β and plays an important role in antiviral immunity. Despite the biological importance of IRF3, its in vivo phosphorylation pattern has not been reported. In this study, we have identified residu...

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Bibliografiske detaljer
Main Authors: Bergstroem, Bjarte, Johnsen, Ingvild B., Nguyen, Thuy Thanh, Hagen, Lars, Slupphaug, Geir, Thommesen, Liv, Anthonsen, Marit W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915726/
https://ncbi.nlm.nih.gov/pubmed/20511230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.084822
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