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Pgrmc1 (Progesterone Receptor Membrane Component 1) Associates with Epidermal Growth Factor Receptor and Regulates Erlotinib Sensitivity

Tumorigenesis requires the concerted action of multiple pathways, including pathways that stimulate proliferation and metabolism. Epidermal growth factor receptor (EGFR) is a transmembrane receptor-tyrosine kinase that is associated with cancer progression, and the EGFR inhibitors erlotinib/tarceva...

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Autors principals: Ahmed, Ikhlas S., Rohe, Hannah J., Twist, Katherine E., Craven, Rolf J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915713/
https://ncbi.nlm.nih.gov/pubmed/20538600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.134585
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