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Inhibition of Golgi Apparatus Glycosylation Causes Endoplasmic Reticulum Stress and Decreased Protein Synthesis

Nucleotide sugar transporters of the Golgi apparatus play an essential role in the glycosylation of proteins, lipids, and proteoglycans. Down-regulation of expression of the transporters for CMP-sialic acid, GDP-fucose, or both unexpectedly resulted in accumulation of glycoconjugates in the Golgi ap...

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Main Authors: Xu, Yu-Xin, Liu, Li, Caffaro, Carolina E., Hirschberg, Carlos B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915696/
https://ncbi.nlm.nih.gov/pubmed/20529871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.134544
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