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Inhibition of Golgi Apparatus Glycosylation Causes Endoplasmic Reticulum Stress and Decreased Protein Synthesis

Nucleotide sugar transporters of the Golgi apparatus play an essential role in the glycosylation of proteins, lipids, and proteoglycans. Down-regulation of expression of the transporters for CMP-sialic acid, GDP-fucose, or both unexpectedly resulted in accumulation of glycoconjugates in the Golgi ap...

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書誌詳細
主要な著者: Xu, Yu-Xin, Liu, Li, Caffaro, Carolina E., Hirschberg, Carlos B.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915696/
https://ncbi.nlm.nih.gov/pubmed/20529871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.134544
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