Essential in Vivo Roles of the C-type Lectin Receptor CLEC-2: EMBRYONIC/NEONATAL LETHALITY OF CLEC-2-DEFICIENT MICE BY BLOOD/LYMPHATIC MISCONNECTIONS AND IMPAIRED THROMBUS FORMATION OF CLEC-2-DEFICIENT PLATELETS

CLEC-2 has been described recently as playing crucial roles in thrombosis/hemostasis, tumor metastasis, and lymphangiogenesis. The snake venom rhodocytin is known as a strong platelet activator, and we have shown that this effect is mediated by CLEC-2 (Suzuki-Inoue, K., Fuller, G. L., García, A., Eb...

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Hauptverfasser: Suzuki-Inoue, Katsue, Inoue, Osamu, Ding, Guo, Nishimura, Satoshi, Hokamura, Kazuya, Eto, Koji, Kashiwagi, Hirokazu, Tomiyama, Yoshiaki, Yatomi, Yutaka, Umemura, Kazuo, Shin, Yonchol, Hirashima, Masanori, Ozaki, Yukio
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915686/
https://ncbi.nlm.nih.gov/pubmed/20525685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.130575
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