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Liganded Thyroid Hormone Receptor-α Enhances Proliferation of Pancreatic β-Cells

Failure of the functional pancreatic β-cell mass to expand in response to increased metabolic demand is a hallmark of type 2 diabetes. Lineage tracing studies indicate that replication of existing β-cells is important for β-cell proliferation in adult animals. In rat pancreatic β-cell lines (RIN5F),...

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Detalhes bibliográficos
Main Authors: Furuya, Fumihiko, Shimura, Hiroki, Yamashita, Sayaka, Endo, Toyoshi, Kobayashi, Tetsuro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915684/
https://ncbi.nlm.nih.gov/pubmed/20529852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.100222
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