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Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells

The mammalian target of rapamycin (mTOR) kinase is an important component of PTEN/PI3K/Akt signaling pathway, which is frequently deregulated in prostate cancer (CaP). Recent studies suggest that targeting PTEN/PI3K/Akt and mTOR signaling pathway could be an effective strategy for the treatment of h...

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Autors principals: Suh, Yewseok, Afaq, Farrukh, Khan, Naghma, Johnson, Jeremy J., Khusro, Fatima H., Mukhtar, Hasan
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915634/
https://ncbi.nlm.nih.gov/pubmed/20530556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq115
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