Genetic variation in the progesterone receptor gene and risk of endometrial cancer: a haplotype-based approach

Background: It is well established that estrogen increases endometrial cancer risk, whereas progesterone opposes the estrogen effects. The PROGINS allele of the progesterone receptor (PGR) gene reduces the function of PGR and has been associated with increased risk of the endometrioid type ovarian c...

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Hlavní autoři: Lee, Eunjung, Hsu, Chris, Haiman, Christopher A., Razavi, Pedram, Horn-Ross, Pamela L., Van Den Berg, David, Bernstein, Leslie, Le Marchand, Loic, Henderson, Brian E., Setiawan, V. Wendy, Ursin, Giske
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
Molecular Epidemiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915632/
https://ncbi.nlm.nih.gov/pubmed/20547493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq113
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