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Endogenous endothelin stimulates cardiac sympathetic afferents during ischaemia

Myocardial ischaemia activates cardiac sympathetic afferents leading to chest pain and reflex cardiovascular responses. Previous studies have shown that a brief period of myocardial ischaemia increases endothelin in cardiac venous plasma draining ischaemic myocardium and that exogenous endothelin ex...

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Bibliographic Details
Main Authors: Fu, Liang-Wu, Guo, Zhi-Ling, Longhurst, John C
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915521/
https://ncbi.nlm.nih.gov/pubmed/20442267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.188730
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