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When is Chemical Similarity Significant? The Statistical Distribution of Chemical Similarity Scores and Its Extreme Values

As repositories of chemical molecules continue to expand and become more open, it becomes increasingly important to develop tools to search them efficiently and assess the statistical significance of chemical similarity scores. Here we develop a general framework for understanding, modeling, predict...

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Détails bibliographiques
Auteurs principaux: Baldi, Pierre, Nasr, Ramzi
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914517/
https://ncbi.nlm.nih.gov/pubmed/20540577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci100010v
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