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Cyclic 1,2-Diketones as Core Building Blocks: A Strategy for the Total Synthesis of (−)-Terpestacin

We report a full account of our work towards the total synthesis of (−)-terpestacin (1), a sesterterpene originally isolated from fungal strain Arthrinium sp. FA1744. Its promising anti-HIV/anti-cancer activity as well as its novel structure make terpestacin an attractive synthetic target. A strateg...

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Detalhes bibliográficos
Main Authors: Trost, Barry M., Dong, Guangbin, Vance, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914478/
https://ncbi.nlm.nih.gov/pubmed/20411537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.200903356
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