Ovine Proinflammatory Cytokines Cross the Murine Blood-Brain Barrier by a Common Saturable Transport Mechanism

OBJECTIVES: The cytokines interleukin (IL)-1β and IL-6 are modulators of the neuroimmune axis and have been implicated in neuronal cell death cascades after ischemia or infection. Previous work has shown that some cross-species conservation exists between human and rodent blood-brain barrier (BBB) t...

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Bibliographic Details
Main Authors: Threlkeld, Steven W., Lynch, Jessica L., Lynch, Kristin M., Sadowska, Grazyna B., Banks, William A., Stonestreet, Barbara S.
Format: Artigo
Language:Inglês
Published: S. Karger AG 2010
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914440/
https://ncbi.nlm.nih.gov/pubmed/20516722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000288265
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