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Changes in 5-HT(2A)-mediated behavior and 5-HT(2A)- and 5-HT(1A) receptor binding and expression in conditional BDNF knock-out mice

Changes in brain-derived neurotrophic factor (BDNF) expression have been implicated in the etiology of psychiatric disorders. To investigate pathological mechanisms elicited by perturbed BDNF signaling, we examined mutant mice with central depletion of BDNF (BDNF(2L/2LCk-cre)). A severe impairment s...

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Detalhes bibliográficos
Main Authors: Klein, AB, Santini, MA, Aznar, S, Knudsen, GM, Rios, M
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914121/
https://ncbi.nlm.nih.gov/pubmed/20576498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.05.054
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