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TLX1 and NOTCH coregulate transcription in T cell acute lymphoblastic leukemia cells
BACKGROUND: The homeobox gene TLX1 (for T-cell leukemia homeobox 1, previously known as HOX11) is inappropriately expressed in a major subgroup of T cell acute lymphoblastic leukemia (T-ALL) where it is strongly associated with activating NOTCH1 mutations. Despite the recognition that these genetic...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2913983/ https://ncbi.nlm.nih.gov/pubmed/20618946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-181 |
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