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Key role for spinal dorsal horn microglial kinin B(1 )receptor in early diabetic pain neuropathy

BACKGROUND: The pro-nociceptive kinin B(1 )receptor (B(1)R) is upregulated on sensory C-fibres, astrocytes and microglia in the spinal cord of streptozotocin (STZ)-diabetic rat. This study aims at defining the role of microglial kinin B(1)R in diabetic pain neuropathy. METHODS: Sprague-Dawley rats w...

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Detalhes bibliográficos
Main Authors: Talbot, Sébastien, Chahmi, Emna, Dias, Jenny Pena, Couture, Réjean
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913947/
https://ncbi.nlm.nih.gov/pubmed/20587056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-7-36
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