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ERK and Not p38 Pathway Is Required for IL-12 Restoration of T Cell IL-2 and IFN-γ in a Rodent Model of Alcohol Intoxication and Burn Injury

Previous studies from our laboratory have shown that acute alcohol/ethanol (EtOH) intoxication combined with burn injury suppresses T cell IL-2 and IFN-γ production by inhibiting p38 and ERK activation. Because IL-12 plays a major role in Th1 differentiation and IFN-γ production, we examined whether...

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Detaylı Bibliyografya
Asıl Yazarlar: Li, Xiaoling, Chaudry, Irshad H., Choudhry, Mashkoor A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913683/
https://ncbi.nlm.nih.gov/pubmed/19710466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804103
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