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Intrauterine administration of endotoxin leads to motor deficits in a rabbit model: a link between prenatal infection and cerebral palsy

OBJECTIVE: To determine whether maternal intrauterine endotoxin administration leads to neurobehavioral deficits in newborn rabbits. STUDY DESIGN: Pregnant New Zealand white rabbits were injected with 1ml saline (n=8) or 20μg/kg of lipolysaccharide in saline (LPS) (n=8) into the uterine wall on day...

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Detalhes bibliográficos
Main Authors: Saadani-Makki, Fadoua, Kannan, Sujatha, Lu, Xin, Janisse, James, Dawe, Elizabeth, Edwin, Samuel, Romero, Roberto, Chugani, Diane
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913549/
https://ncbi.nlm.nih.gov/pubmed/18845289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2008.06.090
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