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MHC class II exacerbates demyelination in vivo independently of T cells
We have shown previously the importance of MHC class II for central nervous system remyelination; however, the function of MHC class II during cuprizone-induced demyelination has not been examined. Here, we show that I-A(β)(−/−) mice exhibit significantly reduced inflammation and demyelination. RAG-...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2913406/ https://ncbi.nlm.nih.gov/pubmed/18805594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2008.06.034 |
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