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Spontaneous Autoimmune Dacryoadenitis in Aged CD25KO Mice

To investigate time-related immunopathological changes in the lacrimal glands (LGs) of CD25KO mice, we examined LGs of C57BL/6 (wild-type) and CD25KO mice at 8, 12, and 16 weeks of age. T cell infiltration was quantified by flow cytometry, and gland function by tear peroxidase activity and epidermal...

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Autors principals: Rahimy, Ehsan, Pitcher, John D., Pangelinan, Solherny B., Chen, Wei, Farley, William J., Niederkorn, Jerry Y., Stern, Michael E., Li, De-Quan, Pflugfelder, Stephen C., De Paiva, Cintia S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913359/
https://ncbi.nlm.nih.gov/pubmed/20566743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091116
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