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Suppression of SLC11A2 Expression Is Essential to Maintain Duodenal Integrity During Dietary Iron Overload

Iron is essential for the survival of mammals, but iron overload causes fibrosis and carcinogenesis. Reduced iron absorption and regulated release into circulation in duodenal mucosa constitute two major mechanisms of protection against dietary iron overload; however, their relative contribution rem...

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Detalhes bibliográficos
Main Authors: Shirase, Tomoyuki, Mori, Kiyoshi, Okazaki, Yasumasa, Itoh, Ken, Yamamoto, Masayuki, Tabuchi, Mitsuaki, Kishi, Fumio, Jiang, Li, Akatsuka, Shinya, Nakao, Kazuwa, Toyokuni, Shinya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913348/
https://ncbi.nlm.nih.gov/pubmed/20558581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090823
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