Tumor Necrosis Factor Receptor Expression and Signaling in Renal Cell Carcinoma

Clear cell renal cell carcinoma (ccRCC), a tubular epithelial cell (TEC) malignancy, frequently secretes tumor necrosis factor (TNF). TNF signals via two distinct receptors (TNFRs). TNFR1, expressed in normal kidney primarily on endothelial cells, activates apoptotic signaling kinase 1 and nuclear f...

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Main Authors: Al-Lamki, Rafia S., Sadler, Timothy J., Wang, Jun, Reid, Martin J., Warren, Anne Y., Movassagh, Mehregan, Lu, Wanhua, Mills, Ian G., Neal, David E., Burge, Johanna, Vandenebeele, Peter, Pober, Jordan S., Bradley, John R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913335/
https://ncbi.nlm.nih.gov/pubmed/20566746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091218
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