Cardiac Progenitor Cells and Biotinylated IGF-1 Nanofibers Improve Endogenous and Exogenous Myocardial Regeneration after Infarction

BACKGROUND: Cardiac progenitor cells (CPCs) possess the IGF-1-IGF-1 receptor system and IGF-1 can be tethered to self-assembling peptide nanofibers (NF-IGF-1) leading to prolonged release of this growth factor to the myocardium. Therefore, we tested whether local injection of clonogenic CPCs and NF-...

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Hauptverfasser: Padin-Iruegas, M. Elena, Misao, Yu, Davis, Michael E., Segers, Vincent F.M., Esposito, Grazia, Tokunou, Tomotake, Urbanek, Konrad, Hosoda, Toru, Rota, Marcello, Anversa, Piero, Leri, Annarosa, Lee, Richard T., Kajstura, Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913250/
https://ncbi.nlm.nih.gov/pubmed/19704095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.852285
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