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Bioequivalence of the 4-mg Oral Granules and Chewable Tablet Formulations of Montelukast

PURPOSE: The primary objective of the studies was to demonstrate bioequivalence between the oral granules formulation and chewable tablet of montelukast in the fasted state. Effect of food on the pharmacokinetics of the oral granules was also evaluated. METHODS: The Formulation Biocomparison Study (...

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Main Authors: Knorr, Barbara, Hartford, Alan, Li, Xiujiang (Susie), Yang, Amy Yifan, Noonan, Gertrude, Migoya, Elizabeth
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Inc 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913109/
https://ncbi.nlm.nih.gov/pubmed/20686624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1753-5174.2010.00029.x
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